DNA-PK


DNA-PKcs (DNA-dependent protein kinase)  is the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase called DNA-PK. The second component is the autoimmune antigen Ku. DNA-PKcs belongs to the phosphatidylinositol 3-kinase-related kinase protein family. 
  • NU7026 EY1404

    NU7026是一种有效的DNA-PK抑制剂,IC50为0.23 μM,作用于DNA-PK比作用于PI3K选择性高60倍,抑制ATM和ATR活性。

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  • KU-0060648 EY0920

    KU-0060648是DNA-PK和PI3Kα/β/δ双重抑制剂,IC50分别为8.6 nM和4 nM/0.5 nM/0.1 nM,对PI3Kγ抑制作用稍弱,IC50为0.59 μM。

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  • NU7026 EY1404

    NU7026是一种有效的DNA-PK抑制剂,IC50为0.23 μM,作用于DNA-PK比作用于PI3K选择性高60倍,抑制ATM和ATR活性。

    More
  • KU-0060648 EY0920

    KU-0060648是DNA-PK和PI3Kα/β/δ双重抑制剂,IC50分别为8.6 nM和4 nM/0.5 nM/0.1 nM,对PI3Kγ抑制作用稍弱,IC50为0.59 μM。

    More
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